P53: FROM FUNDAMENTAL BIOLOGY TO CLINICAL APPLICATIONS IN CANCER

p53: From Fundamental Biology to Clinical Applications in Cancer

p53 tumour suppressor gene is our major barrier against neoplastic transformation.It is involved in many cellular functions, including cell cycle arrest, senescence, DNA repair, apoptosis, autophagy, 2003 kia spectra catalytic converter cell metabolism, ferroptosis, immune system regulation, generation of reactive oxygen species, mitochondrial func

read more

NONENZYMATIC BROWNING KINETIC REACTION AND ASCORBIC ACID DEGREDATION OF HEAT-TREATED ORANGE JUICE DURING STORAGE

The kinetics of ascorbic acid (AA) degradation and nonenzymatic browning (NEB) of heat-treated single strength orange juice (OJ) over a temperature between 70-95 mac miller kids poster oC for 2-10 min.and stored under opaque condition at 4 and 20 oC for 2 months have been studied.Analysis of kinetic data by measuring absorbance at 420 nm (A420) sug

read more

Fishing Nets and String at the Final Mesolithic and Early Neolithic Site of Zamostje 2, Sergiev Posad (Russia)

The site Zamostje 2, located in Sergiev-Posad district of Moscow (Russia) on the west bank of the Dubna River, has provided two Mesolithic and one Early Neolithic occupations dated from 7000 aftermath cabernet sauvignon 2017 to 5400 cal BC.Thanks to the waterlogged environment, the site has an exceptional preservation.The site has yielded fishing s

read more


The Nearctic-Caribbean species Leptotrachelus dorsalis (Fabricius, 1801): Larval descriptions with a diagnosis of immature Ctenodactylini and natural history notes on the genus and tribe (Coleoptera, Carabidae)

Adults and larvae of Leptotrachelus dorsalis (Fabricius), the Sugarcane Savior Beetle, live in association with grasses, the larvae in the appressed wr60 pressure tank leaf axils.Both adult and larval L.dorsalis eat larvae of the Sugarcane Borer, Diatraea saccharalis (Fabricius), and perhaps other insects living in the confines of the leaf sheaths

read more